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Domenico Ghirlandaio: the first performance of a case of acromegaly and rhinophyma

Very interesting is the portrait of Francesco Sassetti in Florence located in the Church of the Holy Trinity, the work of Ghirlandaio. The second character carries the notes left by deformation of the skull, nose and jaw are typical of acromegaly.

Another very interesting work of Ghirlandaio's portrait is the nephew of the old with the Louvre, where in addition to the look of complicity that benevolent grandfather and grandson exchange, stands a very big nose and ugly: there may be a rhinophyma .

Rhinophyma is an expression of a dermatological disease, acne rosacea, which causes an increase in the number and size of sebaceous glands. References

iconographic

Domenico Ghirlandaio (c. 1490) Portrait of Francesco Sassetti, Florence Church of the Holy Trinity
http://www.wga.hu/art/g/ghirland/domenico/5sassett/frescoes/5confir3.jpg

Domenico Ghirlandaio, An old man with his grandson, 1490, Paris, Louvre
http://www.wga.hu/art/g/ghirland/domenico/7panel/08oldman.jpg